Wat is het limbisch systeem m is a collection of brain structures that regulate emotions, motivation, olfaction (sense of smell), behavior and memory. It includes the amygdala, hippocampus, hypothalamus, basal ganglia and cingulate gyrus. The limbic system is a key part of the nervous system and helps with survival instincts, social bonding, emotional responses and memory. It is also involved in long-term memory storage.

The structure that controls fear is the amygdala, a part of the limbic system. The amygdala is responsible for emotion and is particularly active when a person is experiencing a fearful situation for the first time (emotional inexperience). When this area of the limbic system becomes overactive it can lead to anxiety disorders. The interplay between the hippocampus and the amygdala is important in forming memories as well. The hippocampus provides spatial memory, while the amygdala appears to be involved with episodic-autobiographical (EAM) memory.

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Dysfunction of the limbic system is associated with many psychiatric disorders including bipolar, PTSD, and anxiety. The limbic lobes are also the site of a crucial hormone center, which is involved in all aspects of physical health and well-being from mood to overall health, muscle tone, reproduction and sexual function, and even aging. Damage to the limbic lobes can create a negative feedback loop, where stress causes symptoms that damage the limbic lobes and then those symptoms produce even more stress. This cycle can be difficult to overcome without the help of a therapist or psychiatrist.